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Cross-linked hyaluronic acid gel

Oculenis® BioHAnce® Corneal Gel

Composition:
0.75% Cross-linked Hyaluronic Acid
Oculenis offers advanced ocular surface support by helping maintain a favorable environment for natural recovery. Its extended corneal contact time helps provide lasting hydration and protection between applications, while forming a protective barrier that helps cover and support compromised corneal tissue. The preservative-free formulation is well suited for sensitive or damaged eyes, and its clinically studied safety profile helps support long-term ocular surface health and comfort.
Espèces
Pack size:3 mL
Also available in
Part of the range
Ophthalmology

Benefits

  • Extended corneal contact time helps maintain hydration and protection of the ocular surface between applications
  • Forms a protective barrier that helps cover and support compromised corneal tissue
  • Preservative-free formulation reduces the risk of irritation and is well-suited for sensitive or damaged eyes
  • Compatible with other ophthalmic therapies, including antibiotics, for use in a multimodal approach
  • Clinically studied with demonstrated safety and support of ocular surface health

BioHAnce

  • Place 1 to 2 drops directly into the animal's eye twice daily, or as recommended by a veterinarian
  • The natural blinking motion will distribute the product across the eye's surface
  • During application, avoid touching the tip of the bottle to the animal's eye or any other surface

Instructions

  • Place 1 to 2 drops directly into the animal's eye twice daily (or as recommended by a veterinarian). The natural blinking motion will distribute the product across the eye's surface.
  • During application, avoid touching the tip of the bottle to the animal's eye or any other surface.

Indications

  • Oculenis® BioHAnce® Corneal Gel can be used for lubrication and supplemental support of compromised eyes where additional corneal protection and hydration may be beneficial, such as corneal ulcers, wounds, trauma, and following ocular surgery in dogs, cats, and horses.

More Information

  • Oculenis does not contain antibiotics or other ingredients used to treat infections
  • Oculenis is intended to act as a physical barrier meant to provide long lasting lubrication and reduce friction on the ocular surface
  • Read the full instructions for more information. It is recommended that your pet sees a veterinarian when eye injuries are present

References

  • Arad, D., Mordechai, E.M., Goncharov, Y., Ofri, R. and Sebbag, L. (2025), Enhanced Tear Film Concentrations of Cefazolin and Chloramphenicol Using Cross-Linked Hyaluronic Acid in Canine Eyes. Vet Ophthalmol. https://doi.org/10.1111/vop.70013
  • Atzet, S. K., Frankhauser, A. D., Behan, E. K., Mann, B. K. (October 2022). In vitro efficacy, drug release rates, and characterization of crosslinked hyaluronic acid gel drops combined with common ophthalmic therapeutics [Poster]. ACVO Conference, Palm Springs, CA.
  • Grego, Andressa Lopes, et al. “Comparative Fluorophotometric Evaluation of the Ocular Surface Retention Time of CrossLinked and Linear Hyaluronic Acid Ocular Eye Drops on Healthy Dogs - Veterinary Research Communications.” SpringerLink, Springer, 30 Sept. 2024
  • Bedos L, Allbaugh RA, Roy M, Kubai MA, Sebbag L. Precorneal retention time of ocular lubricants measured with fluorophotometry in healthy dogs. Vet Ophthalmol. 2023 Apr;26 Suppl 1:81-88. doi: 10.1111/vop.13065. Epub 2023 Feb 7. PMID: 36749146
  • Williams DL, Wirostko BM. Topical Cross-Linked HA-Based Hydrogel Accelerates Closure of Corneal Epithelial Defects and Repair of Stromal Ulceration in Companion Animals. Invest Ophthalmol Vis Sci. 2017;58:4616–4622. DOI:10.1167/iovs.16-20848.

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